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3BP-3940

3BP-3940 is a highly potent and selective peptide inhibitor of FAP that targets cancer-associated fibroblasts (CAFs) in the tumor microenvironment. 3BP-3940 can be labeled with radionuclides (such as Ga-68) for precise tumor imaging or Lu-177 for the development of targeted anticancer technologies. 3BP-3940 accumulates in tumor lesions and can be used to diagnose and inhibit various solid cancers and CAFs-related diseases[1][2].

Product Specifications

CAS Number

2803421-14-7

UNSPSC

12352209

Target

FAP; Radionuclide-Drug Conjugates (RDCs)

Type

Peptides

Related Pathways

Antibody-drug Conjugate/ADC Related; Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/3bp-3940.html

Purity

99.73

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1[C@@]2([H])N(CCC2)C([C@H](CSCC3=CC(CSCCNC(CN4CCN(CCN(CCN(CC4)CC(O)=O)CC(O)=O)CC(O)=O)=O)=CC(CSC[C@H](NC([C@@H](NC([C@@H](NC([C@](NC([C@@]5([H])N1CCC5)=O)([H])[C@H](O)C)=O)CCC(N)=O)=O)CC6=CC=CC=C6)=O)C(O)=O)=C3)NC(NCCCC)=O)=O

Molecular Formula

C66H98N14O18S3

Molecular Weight

1471.76

References & Citations

[J]

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Isoform

RDC Peptide

Available Sizes

Frequently Asked Questions

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