6 (5H) -Phenanthridinone

6 (5H) -Phenanthridinone is a potent PARP-1 inhibitor and immunomodulator. 6 (5H) -Phenanthridinone inhibits cell proliferation and can be used in cancer research[1].

Product Specifications

CAS Number

[1015-89-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

PARP

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

COVID-19-anti-virus

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/6-5h-phenanthridinone.html

Purity

99.75

Solubility

DMSO : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1NC2=CC=CC=C2C3=C1C=CC=C3

Molecular Formula

C13H9NO

Molecular Weight

195.22

Precautions

H302, H315, H319, H335

References & Citations

[1]Weltin D, et al. Immunosuppressive activities of 6 (5H) -phenanthridinone, a new poly (ADP-ribose) polymerase inhibitor. Int J Immunopharmacol. 1995 Apr;17 (4) :265-71.