6 (5H) -Phenanthridinone
6 (5H) -Phenanthridinone is a potent PARP-1 inhibitor and immunomodulator. 6 (5H) -Phenanthridinone inhibits cell proliferation and can be used in cancer research[1].
Product Specifications
CAS Number
1015-89-0
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
COVID-19-anti-virus
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/6-5h-phenanthridinone.html
Purity
99.75
Solubility
DMSO : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1NC2=CC=CC=C2C3=C1C=CC=C3
Molecular Formula
C13H9NO
Molecular Weight
195.22
Precautions
H302, H315, H319, H335
References & Citations
[1]Weltin D, et al. Immunosuppressive activities of 6 (5H) -phenanthridinone, a new poly (ADP-ribose) polymerase inhibitor. Int J Immunopharmacol. 1995 Apr;17 (4) :265-71.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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