What is the catalog number for MC1568?

The catalog number for MC1568 is HY-16914.

What sizes are available for MC1568?

MC1568 is available in the following size(s): 5 mg, 10 mg, 10 mM - 1 mL, 50 mg, 100 mg.

How many pack sizes does MC1568 come in?

MC1568 is available in 5 different pack sizes.

MC1568 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MC1568?

MC1568 is manufactured by QuantiMol.

What is the estimated delivery time for MC1568?

Estimated delivery time for MC1568 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MC1568?

The safety data sheet for MC1568 is available here: http://file.medchemexpress.com/batch_PDF/HY-16914/MC1568-SDS-MedChemExpress.pdf.

MC1568

MC1568 is a selective class II (IIa) histone deacetylas (HDAC II) inhibitor, used for cancer research.

Product Specifications

CAS Number

852475-26-4

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/MC1568.html

Purity

97.08

Solubility

DMSO : 18.5 mg/mL (ultrasonic; warming)

Smiles

O=C(NO)/C=C/C1=CC=C(/C=C/C(C2=CC=CC(F)=C2)=O)N1C

Molecular Formula

C17H15FN2O3

Molecular Weight

314.31

Precautions

H302, H315, H319, H335

References & Citations

[1]Nebbioso A, et al. Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity ofHDAC-MEF2 complexes. EMBO Rep. 2009 Jul;10 (7) :776-82.|[2]Venza I, et al. Class II-specific histone deacetylase inhibitors MC1568 and MC1575 suppress IL-8 expression in human melanoma cells. Pigment Cell Melanoma Res. 2013 Mar;26 (2) :193-204.|[3]Nebbioso A, et al. HDACs class II-selective inhibition alters nuclear receptor-dependent differentiation. J Mol Endocrinol. 2010 Oct;45 (4) :219-28.|[4]Kassis H, et al. Class IIa histone deacetylases affect neuronal remodeling and functional outcome after stroke. Neurochem Int. 2016 Jun;96:24-31.