Epigoitrin

Epigoitrin is a natural alkaloid that provides protection against influenza infection by reducing the host’s susceptibility to influenza virus under stress. Epigoitrin exerts antiviral activity against influenza A1 virus FM1 via inhibiting virus attachment and multiplication in vitro. Epigoitrin also has lipid-lowering effects[1][3].

Product Specifications

CAS Number

[1072-93-1]

UNSPSC

12352005

Hazard Statement

H228, H315, H319

Target

Influenza Virus

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/epigoitrin.html

Purity

99.91

Solubility

DMSO : 50 mg/mL (ultrasonic) |Ethanol : 3.33 mg/mL (ultrasonic)

Smiles

S=C1O[C@H](C=C)CN1

Molecular Formula

C5H7NOS

Molecular Weight

129.18

Precautions

H228, H315, H319

References & Citations

[1]Luo Z, et al. Epigoitrin, an Alkaloid From Isatis indigotica, Reduces H1N1 Infection in Stress-Induced Susceptible Model in vivo and in vitro. Front Pharmacol. 2019 Feb 7;10:78.|[2]He L, et al. 4 (3H) -Quinazolone regulates innate immune signaling upon respiratory syncytial virus infection by moderately inhibiting the RIG-1 pathway in RAW264.7 cell. Int Immunopharmacol. 2017 Nov;52:245-252. |[3]Li M, et al. Epigoitrin alleviates lipid and glucose metabolic disorders induced by a high-fat diet. Food Funct. 2022 Jul 4;13 (13) :7260-7273.