Furaltadone (hydrochloride)

Furaltadone hydrochloride is an orally active antibacterial agent that can be used for the study of intestinal Salmonella infections. Furaltadone has in vitro inhibitory effects on Staphylococcus. In addition, Furaltadone shows inhibitory effects on allergic reactions[1][2][3].

Product Specifications

CAS Number

[3759-92-0]

Product Name Alternative

Altafur (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Furaltadone-hydrochloride.html

Concentration

10mM

Purity

99.46

Solubility

DMSO : 16.67 mg/mL (ultrasonic) |H2O : ≥ 25 mg/mL

Smiles

O=C1OC(CN2CCOCC2)CN1/N=C/C3=CC=C([N+]([O-])=O)O3.[H]Cl

Molecular Formula

C13H17ClN4O6

Molecular Weight

360.75

Precautions

H302, H315, H319, H335

References & Citations

[1]A.Rampling (Dr.), et al. The effect of furaltadone, a nitrofuran drug, on experimental infections of chickens with salmonella enteritidis phage Type 4. Pathology Volume 25, Supplement 1, 1993, Page 22.|[2]William R. McCabe, et al. Furaltadone — A Critical Evaluation of Clinical and Laboratory Studies. N Engl J Med 1960; 263:927-934.|[3]Nam ST, et al. Furaltadone suppresses IgE-mediated allergic response through the inhibition of Lyn/Syk pathway in mast cells. Eur J Pharmacol. 2018 Jun 5;828:119-125.