(±) 5-HETE lactone

(±) 5-HETE lactone is the racemate of 5-HETE lactone. 5-HETE lactone is a metabolite generated by a series of enzymatic reactions of arachidonic acid, and is also a substrate of paraoxonase-1 (PON1) . 5-HETE lactone can be used in the study of B cell activation[1][2].

Product Specifications

CAS Number

[81517-87-5]

UNSPSC

12352005

Target

Drug Isomer

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/racemic-5-hete-lactone.html

Solubility

10 mM in DMSO

Smiles

CCCCC/C=C\C/C=C\C/C=C\C=C\C1OC(CCC1)=O

Molecular Formula

C20H30O2

Molecular Weight

302.45

References & Citations

[1]Tao C, et al. Reactivity of tricarbonyl (pentadienyl) iron (1+) cations: enantioselective synthesis of 5-HETE methyl ester[J]. The Journal of Organic Chemistry, 1993, 58 (8) : 2134-2143.|[2]Picardo C M. The hydrolysis of 5-HETE lactone by paraoxonase 1 and its stability in serum[M]. 2007.