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(+) -U-50488 (hydrochloride)

(+) -U-50488 (hydrochloride) (+) -Trans- (1R,2R) -U-50488 hydrochloride) is a less active κ opioid receptor (KOR) agonist than the enantiomer of (-) -Trans- (1S,2S) -U-50488 (HY-15997) [1].

Product Specifications

CAS Number

[114528-81-3]

Product Name Alternative

(+) -Trans- (1R,2R) -U-50488 (hydrochloride)

UNSPSC

12352005

Target

Opioid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/plus-u-50488-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

O=C(N(C)[C@H]1[C@H](N2CCCC2)CCCC1)CC3=CC=C(Cl)C(Cl)=C3.[H]Cl

Molecular Formula

C19H27Cl3N2O

Molecular Weight

405.79

References & Citations

[1]DeCosta B, et al. Synthesis and absolute configuration of optically pure enantiomers of a kappa-opioid receptor selective agonist. FEBS Lett. 1987;223 (2) :335-339.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-15997A/plus-U-50488-hydrochloride-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-15997A/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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