CPN-351
CPN-351 (compound 9a), a pentapeptide, is a selective antagonist of human NMUR1 with a pA2 of 7.35. The antagonistic effect of CPN-351 on human NMUR1 is 10 times higher than that on NMUR2. CPN-351 can be used in the study of inflammation[1].
Product Specifications
CAS Number
3057171-63-5
UNSPSC
12352209
Target
Neuromedin U Receptor (NMUR)
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cpn-351.html
Smiles
CN([C@H](C(N[C@@](CC1=CC=CC=C1)(C(N[C@H](C(N2CCC[C@H]2C(N[C@H](C(N)=O)CCCNC(N)=N)=O)=O)CCCNC(N)=N)=O)C)=O)CC3=CNC4=C3C=CC=C4)C(CC5=CC=CS5)=O
Molecular Formula
C45H61N13O6S
Molecular Weight
912.11
References & Citations
[1]akayama K, et al. Discovery of a Pentapeptide Antagonist to Human Neuromedin U Receptor 1. ACS Med Chem Lett. 2024 May 24;15 (6) :885-891.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
NMUR1
Frequently Asked Questions
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