(Rac) -TZ3O

(Rac) -TZ3O is the (Rac) isomer of TZ3O. TZ3O is an anticholinergic compound with neuroprotective activity. TZ3O improves memory impairment and cognitive decline in a scopolamine-induced Alzheimer's disease rat model and can be used in the study of Alzheimer's disease.

Product Specifications

CAS Number

[2218754-19-7]

UNSPSC

12352005

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/rac-tz3o.html

Smiles

O=C1S/C(C(N1CC(C2=CC=CC=C2)=O)=O)=C\C3=CC(O)=CC=C3

Molecular Formula

C18H13NO4S

Molecular Weight

339.37

References & Citations

[1]Taheri M, et al. Neuroprotective Effect of Thiazolidine-2,4-dione Derivatives on Memory Deficits and Neuropathological Symptoms of Dementia on a Scopolamine-Induced Alzheimer's Model in Adult Male Wistar Rats. ACS Chem Neurosci. 2023 Sep 6;14 (17) :3156-3172.