TBT1
TBT1 is a first-generation inhibitor of the MsbA transporter. TBT1 is an LPS transport inhibitor and MsbA ATPase stimulator in strains from the Acinetobacter genus. TBT1 stimulated ATPase activity with an EC50 of 13 µM[1].
Product Specifications
CAS Number
52535-76-9
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/tbt1.html
Purity
99.29
Solubility
DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=C(NC(C2=CC=C(Cl)C=C2)=O)SC3=C1CCCC3)O
Molecular Formula
C16H14ClNO3S
Molecular Weight
335.81
References & Citations
[1]François A Thélot, et al. Distinct allosteric mechanisms of first-generation MsbA inhibitors. Science. 2021 Oct 29;374 (6567) :580-585.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC472981-100 1x 100 µL
Tenascin C (Stromal Marker For Epithelial Malignancy) (TNC/2981R), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details ![Tau (MAPT) Mouse Monoclonal Antibody [Clone ID: OTI6G3]](https://cdn.genprice.uk/products/937/68dd18ba061270361e9084f3/imageurl/cf809144.webp)
CF809144 100 µg
Tau (MAPT) Mouse Monoclonal Antibody [Clone ID: OTI6G3]
Sign In for Pricing
View Details 
21225-AAT 100 Tests
Cell Meter™ Fluorimetric Phagocytosis Assay Kit *Red Fluorescence*
Sign In for Pricing
View Details 
AP21000PU-N 100 µg
VEGF Receptor 2 (KDR) Rabbit Polyclonal Antibody
Sign In for Pricing
View Details 