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MRS3558

MRS3558 is a potent and selective A3AR agonist, with Ki values of 0.6 nM for humans and 0.9 nM for rats, making it suitable for research in the fields of neuropathic pain and anesthesia[1].

Product Specifications

CAS Number

793695-40-6

UNSPSC

12352005

Target

Adenosine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/mrs3558.html

Smiles

CNC([C@]12[C@@H]([C@@H](N3C4=NC(Cl)=NC(NCC5=CC(Cl)=CC=C5)=C4N=C3)[C@H](O)[C@@H]2O)C1)=O

Molecular Formula

C20H20Cl2N6O3

Molecular Weight

463.32

References & Citations

[1]Kiesewetter D O, et al. Synthesis and characterization of [76Br]-labeled high-affinity A3 adenosine receptor ligands for positron emission tomography[J]. Nuclear medicine and biology, 2009, 36 (1) : 3-10.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Adenosine A2A receptor (A2AR)

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