DABCYL-TNF-α-EDANS (-4 to +6) (human)

DABCYL-TNF-α-EDANS (-4 to +6) (human) is a FRET peptide substrate of tumor necrosis factor convertase (TACE) [1].

Product Specifications

CAS Number

[396716-14-6]

Product Name Alternative

TACE Substrate

UNSPSC

12352209

Target

Others

Type

Peptides

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dabcyl-tnf-α-edans-4-to-6-human.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=C(C=C1)/N=N/C2=CC=C(C=C2)N(C)C)N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(NCCNC3=CC=CC4=C3C=CC=C4S(=O)(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C70H104N22O18S

Molecular Weight

1573.78

References & Citations

[1]Liepinsh E, et al. NMR structure of the netrin-like domain (NTR) of human type I procollagen C-proteinase enhancer defines structural consensus of NTR domains and assesses potential proteinase inhibitory activity and ligand binding. J Biol Chem. 2003 Jul 11;278 (28) :25982-9.