20-5,14-HEDGE
20-5,14-HEDGE is a 20-HETE analog. 20-5,14-HEDGE induces cell death in organotypic hippocampal slice cultures (OHSCs) . 20-5,14-HEDGE enhances ROS production and reduces hypoxia-reoxygenation (HR) -induced apoptosis in ex vivo rat lung slices. 20-5,14-HEDGE protects against lung ischemic reperfusion injury in rats. 20-5,14-HEDGE can be used for the study of pulmonary vascular signaling and lung injury-related research[1][2][3].
Product Specifications
CAS Number
1092380-14-7
UNSPSC
12352211
Target
Apoptosis; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/20-5-14-hedge.html
Purity
99.28
Solubility
DMSO : ≥ 100 mg/mL
Smiles
OC(CNC(CCC/C=C\CCCCCCC/C=C\CCCCCO)=O)=O
Molecular Formula
C22H39NO4
Molecular Weight
381.55
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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