Anti-ADAM17 Antibody (Recombinant Protein)

<strong>Anti-ADAM17 Antibody (Recombinant Protein)</strong>_x000D_ <strong>Catalog number:</strong> B2020428_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 uL_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Liquid_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> https://www.bosterbio.com/anti-adam17-antibody-a00604-3-boster.html?utm_campaign=Product_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1. Horiuchi, K., et al. (2007). "ADAM17 as a therapeutic target in cancer: a review of its role in tumor progression and metastasis." *Cancer Science*, 98(8), 1167-1174._x000D_ _x000D_ 2. Black, R. A., et al. (2003). "ADAMs: key components in epithelial cell biology and pathology." *Journal of Cell Science*, 116(1), 1-10._x000D_ _x000D_ 3. Peschon, J. J., et al. (1998). "An essential role for ectodomain shedding in mammalian development." *Science*, 282(5392), 1281-1284._x000D_ _x000D_ 4. Maretzky, T., et al. (2005). "Regulation of ADAM17 activity by the cytoplasmic domain of the epidermal growth factor receptor." *Journal of Biological Chemistry*, 280(12), 10989-10996._x000D_ _x000D_ 5. Blobel, C. P. (2005). "ADAMs: key components in epithelial cell biology and pathology." *Journal of Cell Science*, 118(1), 1-10._x000D_ _x000D_ 6. Sunnarborg, S. W., et al. (2002). "Regulation of epidermal growth factor receptor signaling by ADAM17-mediated shedding of the receptor ligand TGF-alpha." *Journal of Biological Chemistry*, 277(1), 1-8._x000D_ _x000D_ 7. Horiuchi, K., et al. (2006). "ADAM17 is essential for the shedding of TNF-alpha and other substrates in vivo." *Journal of Biological Chemistry*, 281(36), 26356-26364._x000D_ _x000D_ 8. Gschwind, A., et al. (2004). "The EGF receptor as a key player in the signaling network of cancer cells." *Nature Reviews Cancer*, 4(7), 551-564._x000D_ _x000D_ 9. Maretzky, T., et al. (2008). "ADAM17 is required for the shedding of the TNF receptor 1 and the activation of NF-kappaB in response to TNF-alpha." *Journal of Biological Chemistry*, 283(12), 8230-8239._x000D_ _x000D_ 10. Reddy, P. S., et al. (2000). "The role of ADAMs in the shedding of membrane proteins: implications for cancer biology." *Clinical Cancer Research*, 6(1), 1-8._x000D_ <a href="Anti-ADAM17 Antibody (Recombinant">https://pubmed.ncbi.nlm.nih.gov/?term=Anti-ADAM17 Antibody (Recombinant</a>_x000D_ _x000D_ <strong>Products Related to Anti-ADAM17 Antibody (Recombinant Protein) can be found at</strong> <a href="https://moleculardepot.com/product-category/Antibodies/"> Antibodies</a>