Isoguvacine (hydrochloride)

Isoguvacine hydrochloride is a GABA receptor agonist.

Product Specifications

CAS Number

[68547-97-7]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Isoguvacine_hydrochloride.html

Purity

99.81

Solubility

DMSO : 25 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CCNCC1)O.[H]Cl

Molecular Formula

C6H10ClNO2

Molecular Weight

163.60

Precautions

H315, H319, H335

References & Citations

[1]Morin AM, et al. The binding of 3H-isoguvacine to mouse brain synapticmembranes. Life Sci. 1980 Apr 14;26 (15) :1239-45.|[2]White WF, et al. Isoguvacine binding, uptake, and release: relation to the GABA system. J Neurochem. 1983 Jun;40 (6) :1701-8.|[3]Wahab A, et al. Effects of gamma-aminobutyric acid (GABA) agonists and a GABA uptake inhibitor on pharmacoresistant seizure like events in organotypic hippocampal slice cultures. Epilepsy Res. 2009 Oct;86 (2-3) :113-23.