Isoguvacine (hydrochloride)
Isoguvacine hydrochloride is a GABA receptor agonist.
Product Specifications
CAS Number
68547-97-7
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Isoguvacine_hydrochloride.html
Purity
99.81
Solubility
DMSO : 25 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CCNCC1)O.[H]Cl
Molecular Formula
C6H10ClNO2
Molecular Weight
163.60
Precautions
H315, H319, H335
References & Citations
[1]Morin AM, et al. The binding of 3H-isoguvacine to mouse brain synapticmembranes. Life Sci. 1980 Apr 14;26 (15) :1239-45.|[2]White WF, et al. Isoguvacine binding, uptake, and release: relation to the GABA system. J Neurochem. 1983 Jun;40 (6) :1701-8.|[3]Wahab A, et al. Effects of gamma-aminobutyric acid (GABA) agonists and a GABA uptake inhibitor on pharmacoresistant seizure like events in organotypic hippocampal slice cultures. Epilepsy Res. 2009 Oct;86 (2-3) :113-23.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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