Oligomycin A
Oligomycin A (MCH 32), created by Streptomyces, acts as a mitochondrial F0F1-ATPase inhibitor, with a Ki of 1 μM; Oligomycin A shows anti-fungal activity.
Product Specifications
CAS Number
579-13-5
Product Name Alternative
MCH 32
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; ATP Synthase; Fungal
Type
Natural Products
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/Oligomycin_A.html
Purity
99.94
Solubility
DMSO : 100 mg/mL (ultrasonic) |Ethanol : 100 mg/mL (ultrasonic; heat to 60°C)
Smiles
O=C(/C=C/[C@H](C)[C@@H](O)[C@H](C)C([C@H](C)[C@@H](O)[C@@H]1C)=O)O[C@@]([C@@H]2C)([H])[C@H](C)[C@@]3(CC[C@H](C)[C@H](C[C@H](O)C)O3)O[C@@]2([H])CC[C@@H](CC)/C=C/C=C/C[C@@H](C)[C@H](O)[C@@](C)(O)C1=O
Molecular Formula
C45H74O11
Molecular Weight
791.06
Precautions
H302, H315, H319, H335
References & Citations
[1]Salomon AR, et al. Apoptolidin, a selective cytotoxic agent, is an inhibitor of F0F1-ATPase. Chem Biol. 2001 Jan;8 (1) :71-80.|[2]Ramió-Lluch L, et al. Oligomycin A-induced inhibition of mitochondrial ATP-synthase activity suppresses boar sperm motility and in vitro capacitation achievement without modifying overall sperm energy levels. Reprod Fertil Dev. 2014;26 (6) :883-97.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
20328066 1.0 µg DNA
FBXO34 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details 
bs-1020R-BF555 100 µL
ERK1 Polyclonal Antibody, AbBy Fluor™ 555 Conjugated
Sign In for Pricing
View Details 
abx359470 96 Well
Monkey Soluble Vascular Cell Adhesion Molecule 1 (sVCAM-1) ELISA Kit
Sign In for Pricing
View Details