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GLP-1 (28-36) amide

GLP-1 (28-36) amide, a C-terminal nonapeptide of GLP-1, is a major product derived from the cleavage of GLP-1 by the neutral endopeptidase (NEP) . GLP-1 (28-36) amide is an antioxidant and targets to mitochondrion, inhibits mitochondrial permeability transition (MPT) . GLP-1 (28-36) amide has anti-diabetic and cardioprotection effects[1].

Product Specifications

CAS Number

[1225021-13-5]

UNSPSC

12352209

Target

GCGR

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/glp-1-28-36-amide.html

Purity

98.64

Solubility

DMSO : 33.33 mg/mL (ultrasonic)

Smiles

N=C(N)NCCC[C@@H](C(N)=O)NC(CNC([C@H](CCCCN)NC([C@H](C(C)C)NC([C@H](CC(C)C)NC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](C)NC([C@H]([C@@H](C)CC)NC([C@H](CC3=CC=CC=C3)N)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C54H85N15O9

Molecular Weight

1088.35

References & Citations

[1]Bilan Zhou, et al. GLP-1 (28-36) amide, a Long Ignored Peptide Revisited. Open Biochem J. 2014 Dec 31;8:107-11.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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