Human Immunoglobulin J Chain Antibody

<strong>Human Immunoglobulin J Chain Antibody</strong>_x000D_ <strong>Catalog number:</strong> B2015727_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> Joining Chain of Multimeric IgA and IgM, JChain, IGCJ, JCH_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Pankhurst T, Nash G, Williams J, Colman R, Hussain A, Savage C. Immunoglobulin subclass determines ability of immunoglobulin (Ig)G to capture and activate neutrophils presented as normal human IgG or disease-associated anti-neutrophil cytoplasm antibody (ANCA)-IgG Clin Exp Immunol. 2011 May;164(2):218-26._x000D_ 2: Shan L, Colazet M, Rosenthal KL, Yu XQ, Bee JS, Ferguson A, Damschroder MM, Wu H, Dall'Acqua WF, Tsui P, Oganesyan V. Generation and Characterization of an IgG4 Monomeric Fc Platform PLoS One. 2016 Aug 1;11(8):e0160345._x000D_ 3: Rispens T, den Bleker TH, Aalberse RC. Hybrid IgG4/IgG4 Fc antibodies form upon 'Fab-arm' exchange as demonstrated by SDS-PAGE or size-exclusion chromatography Mol Immunol. 2010 Apr;47(7-8):1592-4._x000D_ 4: Lee JI, Choi YJ, Park HJ, Jung KC, Park SH. RD-05, a novel anti-CD154 antibody, efficiently inhibits generation of anti-drug antibody without the risk of thrombus formation in non-human primates Biochem Biophys Res Commun. 2018 Apr 15;498(4):996-1001._x000D_ 5: Tang J, Gao W, Zhang Q, Zhang D, Chen Y, He B, Liu Q. [Expression of human IL-35-IgG4 (Fc) fusion protein in CHO/DG44 cells] Sheng Wu Gong Cheng Xue Bao. 2009 Jan;25(1):109-15._x000D_ 6: Wisniewski J, Agrawal R, Woodfolk JA. Mechanisms of tolerance induction in allergic disease: integrating current and emerging concepts Clin Exp Allergy. 2013 Feb;43(2):164-76._x000D_ 7: Prodjinotho UF, Hoerauf A, Adjobimey T. IgG4 antibodies from patients with asymptomatic bancroftian filariasis inhibit the binding of IgG1 and IgG2 to C1q in a Fc-Fc-dependent mechanism Parasitol Res. 2019 Oct;118(10):2957-2968._x000D_ 8: Jung BK, An Y, Park JE, Chang KS, Jang H. Development of a recombinant vaccine containing a spike S1-Fc fusion protein induced protection against MERS-CoV in human DPP4 knockin transgenic mice J Virol Methods. 2022 Jan;299:114347._x000D_ 9: Corper AL, Sohi MK, Bonagura VR, Steinitz M, Jefferis R, Feinstein A, Beale D, Taussig MJ, Sutton BJ. Structure of human IgM rheumatoid factor Fab bound to its autoantigen IgG Fc reveals a novel topology of antibody-antigen interaction Nat Struct Biol. 1997 May;4(5):374-81._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/37031320">10: Svilenov HL, Delhommel F, Siebenmorgen T, Rührnößl F, Popowicz GM, Reiter A, Sattler M, Brockmeyer C, Buchner J. Extrinsic stabilization of antiviral ACE2-Fc fusion proteins targeting SARS-CoV-2 Commun Biol. 2023 Apr 8;6(1):386. </a>_x000D_ _x000D_ <strong>Products Related to Human Immunoglobulin J Chain Antibody can be found at</strong> <a href="https://moleculardepot.com/product-category/Antibodies/"> Antibodies</a>