Ac-Atovaquone
Ac-Atovaquone is a potent cytochrome bc1 inhibitor and also is an ester-linked acetyl derivative of Atovaquone. Ac-Atovaquone has the potential for the research of malaria[1][1][2].
Product Specifications
CAS Number
129700-44-3
UNSPSC
12352101
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ac-atovaquone.html
Smiles
O=C1C([C@H]2CC[C@H](C3=CC=C(Cl)C=C3)CC2)=C(OC(C)=O)C(C4=CC=CC=C41)=O
Molecular Formula
C24H21ClO4
Molecular Weight
408.87
References & Citations
[1]Siqueira-Neto JL, et al. Antimalarial drug discovery: progress and approaches. Nat Rev Drug Discov. 2023 Oct;22 (10) :807-826. doi: 10.1038/s41573-023-00772-9. Epub 2023 Aug 31. Erratum in: Nat Rev Drug Discov. 2024 Nov;23 (11) :880.|[2]El Gaaloul M, et al. Chemoprevention of malaria with long-acting oral and injectable drugs: an updated target product profile. Malar J. 2024 Oct 18;23 (1) :315.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Frequently Asked Questions
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