STF-118804
Product Specifications
UNSPSC Description
STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.
Target Antigen
Apoptosis; NAMPT
Type
Reference compound
Related Pathways
Apoptosis;Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/STF-118804.html
Purity
99.72
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(NCC1=CC=CN=C1)C2=CC=C(C3=NC(CS(=O)(C4=CC=C(C)C=C4)=O)=C(C)O3)C=C2
Molecular Weight
461.543
References & Citations
[1]Matheny CJ, et al. Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens. Chem Biol. 2013 Nov 21;20(11):1352-63.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-12808/STF-118804-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-12808/STF-118804-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
894187-61-2
Available Sizes
Curated Selection
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