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STF-118804

Product Specifications

UNSPSC Description

STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.

Target Antigen

Apoptosis; NAMPT

Type

Reference compound

Related Pathways

Apoptosis;Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/STF-118804.html

Purity

99.72

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C(NCC1=CC=CN=C1)C2=CC=C(C3=NC(CS(=O)(C4=CC=C(C)C=C4)=O)=C(C)O3)C=C2

Molecular Weight

461.543

References & Citations

[1]Matheny CJ, et al. Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens. Chem Biol. 2013 Nov 21;20(11):1352-63.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-12808/STF-118804-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-12808/STF-118804-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

894187-61-2

Available Sizes

Curated Selection

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