Ortataxel
Ortataxel (IDN 5109; BAY 59-8862) is a derivative of Paclitaxel. Ortataxel exhibits activity against multiple drug-sensitive and resistant cancer cell lines[1].
Product Specifications
CAS Number
186348-23-2
Product Name Alternative
IDN 5109; BAY 59-8862
UNSPSC
12352005
Hazard Statement
H301-H331
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ortataxel.html
Smiles
CC(C)C[C@H](NC(OC(C)(C)C)=O)[C@@H](O)C(O[C@@H]([C@]1([H])OC(O[C@@]12[C@@H](OC(C3=CC=CC=C3)=O)[C@@]4([H])[C@@]5(C)[C@@H](O)C[C@]6([H])[C@@]4(OC(C)=O)CO6)=O)C(C)=C(C2(C)C)[C@@H](OC(C)=O)C5=O)=O
Molecular Formula
C44H57NO17
Molecular Weight
871.92
Precautions
P261-P264-P270-P271-P304+P340-P330-P403+P233-P405-P501
References & Citations
[1]Xiang F, et al., Structure-activity relationship of taxol inferring from docking taxol analogues to microtubule binding site. Z Naturforsch C J Biosci. 2009 Jul-Aug;64 (7-8) :551-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Frequently Asked Questions
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