Ortataxel

Ortataxel (IDN 5109; BAY 59-8862) is a derivative of Paclitaxel (HY-B0015) . Ortataxel exhibits activity against multiple drug-sensitive and resistant cancer cell lines[1].

Product Specifications

CAS Number

[186348-23-2]

Product Name Alternative

IDN 5109; BAY 59-8862

UNSPSC

12352005

Hazard Statement

H301-H331

Target

Microtubule/Tubulin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ortataxel.html

Smiles

CC(C)C[C@H](NC(OC(C)(C)C)=O)[C@@H](O)C(O[C@@H]([C@]1([H])OC(O[C@@]12[C@@H](OC(C3=CC=CC=C3)=O)[C@@]4([H])[C@@]5(C)[C@@H](O)C[C@]6([H])[C@@]4(OC(C)=O)CO6)=O)C(C)=C(C2(C)C)[C@@H](OC(C)=O)C5=O)=O

Molecular Formula

C44H57NO17

Molecular Weight

871.92

Precautions

P261-P264-P270-P271-P304+P340-P330-P403+P233-P405-P501

References & Citations

[1]Xiang F, et al., Structure-activity relationship of taxol inferring from docking taxol analogues to microtubule binding site. Z Naturforsch C J Biosci. 2009 Jul-Aug;64 (7-8) :551-6.