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Anti-Rat CD28 Antibody (JJ316)

Anti-Rat CD28 Antibody (JJ316) is a mouse-derived agonistic IgG1 κ type antibody, targeting to rat CD28. Anti-Rat CD28 Antibody (JJ316) can induce T cell proliferation. Anti-Rat CD28 Antibody (JJ316) can be used for the researches of inflammation, immunology and neurological disease, such as experimental autoimmune encephalomyelitis (EAE) and graft-versus-host disease (GvHD) [1][2].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352203

Target

CD28

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/anti-rat-cd28-antibody-jj316.html

Smiles

[Anti-RatCD28Antibody(JJ316)]

Molecular Weight

(150 kDa)

References & Citations

[1]Beyersdorf N, et al. Selective targeting of regulatory T cells with CD28 superagonists allows effective therapy of experimental autoimmune encephalomyelitis. J Exp Med. 2005 Aug 1;202 (3) :445-55.|[2]Kitazawa Y, et al. Superagonist CD28 antibody preferentially expanded Foxp3-expressing nTreg cells and prevented graft-versus-host diseases. Cell Transplant. 2009;18 (5) :627-37.

Shipping Conditions

Room temperature

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Frequently Asked Questions

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