D4R antagonist-2
D4R antagonist-2 (compound 33) is a D4R antagonist. D4R antagonist-2 has a IC50 value of 210 nM, and a Ki value of 59 nM for D4R. D4R antagonist-2 can be used in the Parkinson's disease research[1].
Product Specifications
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/d4r-antagonist-2.html
Smiles
O=C(N1CC2(CCN(CC3=CNC4=C3C=CC(F)=C4)CC2)C1)C5=CC=CC=C5C
Molecular Formula
C24H26FN3O
Molecular Weight
391.48
References & Citations
[1]Jones CAH, et al. Computer-Aided Design and Biological Evaluation of Diazaspirocyclic D4R Antagonists. ACS Chem Neurosci. 2024 Jun 19;15 (12) :2396-2407.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D4 Receptor
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TRV-0057369-01 20 µL
Polyclonal Antibody to Histone Deacetylase 2 (HDAC2)
Sign In for Pricing
View Details TRV-0057369-02 100 µL
Polyclonal Antibody to Histone Deacetylase 2 (HDAC2)
Sign In for Pricing
View Details TRV-0057369-03 200 µL
Polyclonal Antibody to Histone Deacetylase 2 (HDAC2)
Sign In for Pricing
View Details TRV-0057369-04 1 mL
Polyclonal Antibody to Histone Deacetylase 2 (HDAC2)
Sign In for Pricing
View Details