L-Ent-oxPt(IV)
Product Specifications
UNSPSC Description
L-Ent-oxPt IV (L-EOP) is a Oxaliplatin (HY-17371)-based siderophore-platinum conjugate. L-Ent-oxPt IV exhibits selectivity towards Escherichia coli and antibacterial activity through DNA damage[1].
Target Antigen
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/l-ent-oxpt-iv.html
Solubility
10 mM in DMSO
Smiles
CC(O[Pt]1(OC2=O)(OC2=O)(OC(CCC3=CN(CCOCCOCCOCCNC(C4=CC(C(N[C@@H](CO5)C(OC[C@@H](C(OC[C@H](NC(C6=C(O)C(O)=CC=C6)=O)C5=O)=O)NC(C7=C(O)C(O)=CC=C7)=O)=O)=O)=C(O)C(O)=C4)=O)N=N3)=O)[NH2][C@@H]8CCCC[C@H]8[NH2]1)=O
Molecular Weight
1467.22
References & Citations
[1]Guo C, et al., Investigation of Siderophore-Platinum(IV) Conjugates Reveals Differing Antibacterial Activity and DNA Damage Depending on the Platinum Cargo. ACS Infect Dis. 2024 Mar 4.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163383/L-Ent-oxPt-IV-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163383/
Clinical Information
No Development Reported
Curated Selection
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