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L-Ent-oxPt (IV)

L-Ent-oxPt IV (L-EOP) is a Oxaliplatin (HY-17371) -based siderophore-platinum conjugate. L-Ent-oxPt IV exhibits selectivity towards Escherichia coli and antibacterial activity through DNA damage[1].

Product Specifications

Product Name Alternative

L-EOP

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/l-ent-oxpt-iv.html

Solubility

10 mM in DMSO

Smiles

CC(O[Pt]1(OC2=O)(OC2=O)(OC(CCC3=CN(CCOCCOCCOCCNC(C4=CC(C(N[C@@H](CO5)C(OC[C@@H](C(OC[C@H](NC(C6=C(O)C(O)=CC=C6)=O)C5=O)=O)NC(C7=C(O)C(O)=CC=C7)=O)=O)=O)=C(O)C(O)=C4)=O)N=N3)=O)[NH2][C@@H]8CCCC[C@H]8[NH2]1)=O

Molecular Formula

C54H65N9O27Pt

Molecular Weight

1467.22

References & Citations

[1]Guo C, et al., Investigation of Siderophore-Platinum (IV) Conjugates Reveals Differing Antibacterial Activity and DNA Damage Depending on the Platinum Cargo. ACS Infect Dis. 2024 Mar 4.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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