Anti-Mouse DR5/CD262 Antibody (MD5-1)
Anti-Mouse DR5/CD262 Antibody (MD5-1) is an anti-mouse DR5/CD262 IgG monoclonal antibody. Anti-Mouse DR5/CD262 Antibody (MD5-1) can eliminate myeloid derived suppressor cells (MDSCs) and enhance T cell anti-tumor immunity. Anti-Mouse DR5/CD262 Antibody (MD5-1) can be used for research on cancer such as gastric and colon cancer[1][2].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352203
Target
TNF Receptor
Type
Inhibitory Antibodies
Related Pathways
Apoptosis
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-mouse-dr5-cd262-antibody-md5-1.html
Solubility
10 mM in DMSO
Smiles
[Anti-MouseDR5/CD262Antibody(MD5-1)]
Molecular Weight
(150 kDa)
References & Citations
[1]Yi M, et al. Blockade of CCR5+ T Cell Accumulation in the Tumor Microenvironment Optimizes Anti-TGF-β/PD-L1 Bispecific Antibody. Adv Sci (Weinh) . 2024 Nov;11 (43) :e2408598.|[2]Tang Y, et al. Targeting depletion of myeloid-derived suppressor cells potentiates PD-L1 blockade efficacy in gastric and colon cancers. Oncoimmunology. 2022 Oct 13;11 (1) :2131084.
Shipping Conditions
Room temperature
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Frequently Asked Questions
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