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PBR28

PBR28 is an TSPO modulator, which can be used for prevention research of Pulmonary Arterial Hypertension (PAH) . PBR28 can be used to trace 18 KDa transporter (TSPO) by adding radioactive labeling, which plays an important role in brain positron emission tomography (PET) imaging studies[1].

Product Specifications

CAS Number

253307-65-2

UNSPSC

12352005

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/pbr28.html

Purity

98.91

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C)N(CC1=C(OC)C=CC=C1)C2=C(OC3=CC=CC=C3)C=CN=C2

Molecular Formula

C21H20N2O3

Molecular Weight

348.40

References & Citations

[1]Sander CY, et al. [11C]PBR28 radiotracer kinetics are not driven by alterations in cerebral blood flow. J Cereb Blood Flow Metab. 2021 Nov;41 (11) :3069-3084.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Available Sizes

Frequently Asked Questions

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