PDE4B rabbit pAb
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],
Product Specifications
Background
Gene ID
5142
UniProt
Q07343
Cellular Locus
[Isoform PDE4B5]: Cytoplasm. Cell membrane.
Host
Rabbit
Species Reactivity
Human,Rat
Reactivity
Human; Rat
Immunogen
Synthesized peptide derived from human PDE4B AA range: 103-153
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB
Validated Applications
WB
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1: 500-2000
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES14187-1.pdf
Subcellular Location
[Isoform PDE4B5]: Cytoplasm . Cell membrane .
Gene ID (Human)
5142
SwissProt (Human)
Q07343
Available Sizes
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