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D-Glucosyl-β-N-palmitoylsphingosine-d3

D-Glucosyl-β-N-palmitoylsphingosine-d3 (N-ω-CD3-Hexadecaoyl-glucopsychosie) is deuterium labeled D-Glucosyl-β-1,1′-N-palmitoylsphingosine. D-Glucosyl-β-1,1′-N-palmitoylsphingosine (C16 Glucosyl (β) Ceramide (d18:1/16:0) ) is an endogenous Mincle ligand possessing immunostimulatory activity[1][1][2].

Product Specifications

CAS Number

71924-12-4

Product Name Alternative

N-ω-CD3-Hexadecaoyl-glucopsychosie; GluCe (d18:1/16:0-d3) ; Glucosylceamide-d3 (d18:1/16:0-d3)

UNSPSC

12352005

Target

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Smiles

CCCCCCCCCCCCC/C=C/[C@@H](O)[C@@H](NC(CCCCCCCCCCCCCCC([2H])([2H])[2H])=O)CO[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO

Molecular Formula

C40H74D3NO8

Molecular Weight

703.06

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Nagata M, et, al. Intracellular metabolite β-glucosylceramide is an endogenous Mincle ligand possessing immunostimulatory activity. Proc Natl Acad Sci U S A. 2017 Apr 18;114 (16) :E3285-E3294.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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