MP 518
MP 518 is a PDE inhibitor with antihypertensive properties. MP 518 can inhibit cAMP degradation, causing an increase in ICa, and can also antagonize β-adrenergic stimulation, exerting vasodilation[1].
Product Specifications
CAS Number
122432-93-3
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/mp-518.html
Smiles
O=C(N/N=C(C1=CC=CC=C1Cl)\C)CO
Molecular Formula
C10H11ClN2O2
Molecular Weight
226.66
References & Citations
[1]Scamps F, et al. Effect of an antihypertensive hydrazine derivative on Ca2+ current of single frog cardiac cells. Eur J Pharmacol. 1993 Jan 15;244 (2) :119-23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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