Elodeoidileon A
Elodeoidileon A is an agonist for RXRα, that interacts with RXRα-LBD protein with a dissociation constant Kd of 5.85 μM. Elodeoidileon A promotes the expression of ATP-binding cassette transporter A1 (ABCA1) . Elodeoidileon A reveals the potential in Alzheimer's disease research[1].
Product Specifications
UNSPSC
12352005
Target
RAR/RXR
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/elodeoidileon-a.html
Smiles
C[C@]1(O2)[C@](C(C)(C)[C@H](O)CC1)([H])CC3=C2C(C)(C)C(C(C(C(C)C)=O)=C3O)=O
Molecular Formula
C22H32O5
Molecular Weight
376.49
References & Citations
[1]Li JD, et al., Filicinic acid based meroterpenoids from Hypericum elodeoides and their anti-Alzheimer's disease effects. Bioorg Chem. 2024 Sep 2;153:107787.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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