(iodo-125) -CGP 71872

(iodo-125) -CGP 71872 is a iodo-125-labeled CGP 71872 (GABABR1 receptor agonist), containing an azido group that can be photoactivated, and can be used to characterize GABAB receptors[1].

Product Specifications

CAS Number

[200402-51-3]

UNSPSC

12352005

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/iodo-125-cgp-71872.html

Smiles

O=C(C1=CC=CC([C@@H](C)NC[C@@H](CP(O)(CCCCCNC(C2=CC([125I])=C(C=C2O)N=[N+]=[N-])=O)=O)O)=C1)O

Molecular Formula

C24H31IN5O7P

Molecular Weight

657.41

References & Citations

[1]Belley M, Sullivan R, Reeves A, Evans J, et al. Synthesis of the nanomolar photoaffinity GABA (B) receptor ligand CGP 71872 reveals diversity in the tissue distribution of GABA (B) receptor forms. Bioorg Med Chem. 1999;7 (12) :2697-2704.