MG624
MG624 is a potent and selective neuronal α7 nAChR antagonist with a Ki of 106 nM[1].
Product Specifications
CAS Number
[77257-42-2]
Product Name Alternative
Stilonium iodide
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
NAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mg624.html
Purity
97.30
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC[N+](CC)(CC)CCOC1=CC=C(/C=C/C2=CC=CC=C2)C=C1.[I-]
Molecular Formula
C22H30INO
Molecular Weight
451.38
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Maggi L, et al. Selective effects of a 4-oxystilbene derivative on wild and mutant neuronal chick alpha7 nicotinic receptor. Br J Pharmacol. 1999 Jan;126 (1) :285-95.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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