Taxiphyllin

Taxiphyllin (2R-Taxiphyllin) is a plant cyanogenic glycoside, which exhibits inhibitory activity for tyrosinase[2]. Taxiphyllin exhibits cytotoxicity in BRL-3A cellls with an IC50 of 18.75 μm[3] and antimicrobial activities against Staphylococcus aureus with an EC50 of 0.96 μM[4].

Product Specifications

CAS Number

[21401-21-8]

Product Name Alternative

(2R) -Taxiphyllin

UNSPSC

12352005

Target

Tyrosinase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/taxiphyllin.html

Solubility

10 mM in DMSO

Smiles

N#C[C@@H](C(C=C1)=CC=C1O)O[C@@H]([C@@H]([C@H]2O)O)O[C@@H]([C@H]2O)CO

Molecular Formula

C14H17NO7

Molecular Weight

311.29

References & Citations

[1]Yang CJ, et al. Two new cyanogenic glucosides from the leaves of Hydrangea macrophylla. Molecules. 2012;17 (5) :5396-5403.|[2]Wu B. Tyrosinase inhibitors from terrestrial and marine resources. Curr Top Med Chem. 2014;14 (12) :1425-49.|[3]Yi JJ, et al., Characterisation and in vitro cytotoxicity of toxic and degradation compounds in bamboo shoots (Dendrocalamus Sinicus) during traditional fermentation. Int J of Food Sci Tech. 2020|[4]Oueslati MH, et al., Phytochemical constituents from Salsola tetrandra. J Nat Prod. 2006 Sep;69 (9) :1366-9.