FLQY2
FLQY2 is a camptothecin analog that exhibits outstanding antitumor efficacy against various solid tumors. FLQY2 possesses both in vitro and in vivo anti-pancreatic cancer activity, inhibiting cell proliferation, colony formation, inducing apoptosis, and causing cell cycle arrest at nanomolar concentrations[1][2].
Product Specifications
CAS Number
794512-88-2
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/flqy2.html
Smiles
O=C1C2=C([C@](CC)(O)C(OC2)=O)C=C3C4=NC5=CC6=C(OCO6)C=C5C(C7=CC=C(C(F)(F)F)C=C7)=C4CN31
Molecular Formula
C28H19F3N2O6
Molecular Weight
536.46
References & Citations
[1]Wang W, et al. Biological impact and therapeutic potential of a novel camptothecin derivative (FLQY2) in pancreatic cancer through inactivation of the PDK1/AKT/mTOR pathway[J]. Bioorganic Chemistry, 2024, 148: 107436.|[2]Wang Y, et al. Preparation of a camptothecin analog FLQY2 self-micelle solid dispersion with improved solubility and bioavailability[J]. Journal of Nanobiotechnology, 2022, 20 (1) : 402.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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