Hyuganin D

Hyuganin D (Isobocconin) is a Coumarin (HY-N0709) constituent that substantially inhibits LPS (HY-D1056) -induced NO production in mouse peritoneal macrophages[1].

Product Specifications

CAS Number

[77331-76-1]

Product Name Alternative

Isobocconin; Seravschanin

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/hyuganin-d.html

Solubility

10 mM in DMSO

Smiles

CC(C)C(O[C@@H]1C2=C(O3)C(C=CC3=O)=CC=C2OC(C)(C)[C@@H]1OC(C)=O)=O

Molecular Formula

C20H22O7

Molecular Weight

374.38

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Yoshikawa M, et al. Inhibitory effects of coumarin and acetylene constituents from the roots of Angelica furcijuga on D-galactosamine/lipopolysaccharide-induced liver injury in mice and on nitric oxide production in lipopolysaccharide-activated mouse peritoneal macrophages. Bioorg Med Chem. 2006 Jan 15;14 (2) :456-63.