Sapintoxin A
Sapintoxin A is a phorbol ester that can be isolated from the unripe fruits of Sapium indicum. Sapintoxin A is an activator of the phorbol ester receptor PKC (Ka=76 nM) [1].
Product Specifications
CAS Number
79083-69-5
UNSPSC
12352005
Target
PKC
Type
Natural Products
Related Pathways
Epigenetics; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/sapintoxin-a.html
Smiles
CC(O[C@@]12[C@@]([C@@]3([H])[C@]([C@@H]([C@H]2OC(C4=C(C=CC=C4)NC)=O)C)([C@@]5([H])[C@](C(C(C)=C5)=O)([H])CC(CO)=C3)O)([H])C1(C)C)=O
Molecular Formula
C30H37NO7
Molecular Weight
523.62
References & Citations
[1]Taylor SE, et al. Sapintoxin A, a new biologically active nitrogen containing phorbol ester. Experientia. 1981;37 (7) :681-2.|[2]Brooks G, et al. Sapintoxin A. A fluorescent phorbol ester that is a potent activator of protein kinase C but is not a tumour promoter. Cancer Lett. 1987 Dec;38 (1-2) :165-70.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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