Thalidomide-O-C5-piperidine-NH-Boc
Thalidomide-O-C5-piperidine-NH-Boc is an E3 Ligase Ligand-Linker Conjugate. Thalidomide-O-C5-piperidine-NH-Boc can be used to synthesize PROTAC PIN1 degrader-1.
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/thalidomide-o-c5-piperidine-nh-boc.html
Smiles
O=C1C2=C(C(OCCCCCN3CCC(NC(OC(C)(C)C)=O)CC3)=CC=C2)C(N1C(C(N4)=O)CCC4=O)=O
Molecular Formula
C28H38N4O7
Molecular Weight
542.62
References & Citations
[1]Liu C, et al. Re-Evaluating PIN1 as a Therapeutic Target in Oncology Using Neutral Inhibitors and PROTACs. J Med Chem. 2024 Sep 12;67 (17) :15780-15795.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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