PP 3
Product Specifications
UNSPSC Description
PP 3 (Compound 3) is an EGFR tyrosine kinase inhibitor with an IC50 of 2.7 μM[1].
Target Antigen
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pp-3.html
Purity
98.78
Solubility
DMSO : ≥ 100 mg/mL
Smiles
NC1=C2C(N(C3=CC=CC=C3)N=C2)=NC=N1
Molecular Weight
211.228
References & Citations
[1]Traxler P, et al. Use of a pharmacophore model for the design of EGF-R tyrosine kinase inhibitors: 4-(phenylamino)pyrazolo[3,4-d]pyrimidines. J Med Chem. 1997 Oct 24;40(22):3601-16.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-108484/PP-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-108484/PP-3-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
5334-30-5
Available Sizes
Curated Selection
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