Dichlorogelignate
Dichlorogelignate (compound 4) is a selective inhibitor of topoisomerase II (Topo II) . Dichlorogelignate has 100% inhibition at 50 μM[1].
Product Specifications
CAS Number
164030-91-5
UNSPSC
12352005
Target
Topoisomerase
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dichlorogelignate.html
Solubility
10 mM in DMSO
Smiles
OC([C@](O)(C[C@H]([C@H]1O)O)C[C@H]1OC([C@H]2[C@H](C3=CC(O)=C(C=C3)O)C4=CC(O)=C(O)C=C4C=C2C(O[C@@H]5C[C@@](O)(C[C@H]([C@H]5O)O)C(O)=O)=O)=O)=O
Molecular Formula
C32H34O18
Molecular Weight
706.60
References & Citations
[1]Kashiwada Y, Bastow K F, Lee K H. Novel lignan derivatives as selective inhibitors of DNA topoisomerase II[J]. Bioorganic & Medicinal Chemistry Letters, 1995, 5 (8) : 905-908.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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