Dichlorogelignate
Dichlorogelignate (compound 4) is a selective inhibitor of topoisomerase II (Topo II) . Dichlorogelignate has 100% inhibition at 50 μM[1].
Product Specifications
CAS Number
164030-91-5
UNSPSC
12352005
Target
Topoisomerase
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dichlorogelignate.html
Solubility
10 mM in DMSO
Smiles
OC([C@](O)(C[C@H]([C@H]1O)O)C[C@H]1OC([C@H]2[C@H](C3=CC(O)=C(C=C3)O)C4=CC(O)=C(O)C=C4C=C2C(O[C@@H]5C[C@@](O)(C[C@H]([C@H]5O)O)C(O)=O)=O)=O)=O
Molecular Formula
C32H34O18
Molecular Weight
706.60
References & Citations
[1]Kashiwada Y, Bastow K F, Lee K H. Novel lignan derivatives as selective inhibitors of DNA topoisomerase II[J]. Bioorganic & Medicinal Chemistry Letters, 1995, 5 (8) : 905-908.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC941219-500 1x 500 µL
Cytokeratin 8 (B22.1), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
TRC-E917380-250MG 250 mg
4-Ethyl-N,N-diphenyl-1-naphthalenecarboxamide
Sign In for Pricing
View Details 
BNUM0896-50 1x 50 µL
PDCD1 / PD1 / CD279 (Programmed Cell Death 1) (NAT105), 1mg/mL
Sign In for Pricing
View Details