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CypK

Product Specifications

UNSPSC Description

CypK (N-Cyclopropene-L-Lysine), a cyclopropene derivative of lysine, is efficiently incorporated into antibodies through genetic-code expansion. CypK is a minimal bioorthogonal handle for the creation of stable therapeutic protein conjugates[1][2].

Target Antigen

Others

Type

Reference compound

Related Pathways

Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cypk.html

Smiles

N[C@@H](CCCCNC(OCC1C(C)=C1)=O)C(O)=O

Molecular Weight

256.30

References & Citations

[1]Oller-Salvia B. Genetic Encoding of a Non-Canonical Amino Acid for the Generation of Antibody-Drug Conjugates Through a Fast Bioorthogonal Reaction. J Vis Exp. 2018 Sep 14;(139):58066.|[2]Oller-Salvia B, et, al. Rapid and Efficient Generation of Stable Antibody-Drug Conjugates via an Encoded Cyclopropene and an Inverse-Electron-Demand Diels-Alder Reaction. Angew Chem Int Ed Engl. 2018 Mar 5;57(11):2831-2834.

Shipping Conditions

Blue Ice

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-134669/CypK-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-134669/CypK-SDS-MedChemExpress.pdf

CAS Number

1610703-09-7

Available Sizes

Curated Selection

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