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Conivaptan (hydrochloride) (Standard)

Conivaptan (hydrochloride) (Standard) is the analytical standard of Conivaptan (hydrochloride) . This product is intended for research and analytical applications. Conivaptan (hydrochloride) is a non-peptide antagonist of vasopressin receptor, with Ki values of 0.48 and 3.04 nM for rat liver V1A receptor and rat kidney V2 receptor respectively.

Product Specifications

CAS Number

168626-94-6

Product Name Alternative

YM 087 (Standard)

UNSPSC

12352005

Target

Reference Standards; Vasopressin Receptor

Type

Reference Standards

Related Pathways

GPCR/G Protein; Others

Field of Research

Cardiovascular Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/conivaptan-hydrochloride-standard.html

Smiles

O=C(C1=CC=CC=C1C2=CC=CC=C2)NC3=CC=C(C(N4CCC(N=C(C)N5)=C5C6=CC=CC=C64)=O)C=C3.Cl

Molecular Formula

C32H27ClN4O2

Molecular Weight

535.04

References & Citations

[1]Wada K, et al. Intravenous administration of conivaptan hydrochloride improves cardiac hemodynamics in rats with myocardial infarction-induced congestive heart failure. Eur J Pharmacol. 2005 Jan 10;507 (1-3) :145-51. Epub 2005 Jan 1.|[2]Fernandez-Varo G, et al. Effect of the V1a/V2-AVP receptor antagonist, Conivaptan, on renal water metabolism and systemic hemodynamics in rats with cirrhosis and ascites. J Hepatol. 2003 Jun;38 (6) :755-61.|[3]Yatsu T, et al. Cardiovascular and renal effects of conivaptan hydrochloride (YM087), a vasopressin V1A and V2 receptor antagonist, in dogs with pacing-induced congestive heart failure. Eur J Pharmacol. 1999 Jul 9;376 (3) :239-46.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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