(-) - (E) -Guggulsterone (Standard)
(-) - (E) -guggulsterone (Standard) is the analytical standard for (-) - (E) -guggulsterone ((E) -Guggulsterone). (-) - (E) -Guggulsterone is an orally active natural stereoisomer of Guggulsterone (HY-107738). (-) - (E) -Guggulsterone is an antagonist for the Farnesoid X Receptor (FXR) with an IC50 of 24.06 μM and possesses potent hypolipidemic properties. (-) - (E) -Guggulsterone suppresses dengue virus (DENV) replication by upregulating antiviral interferon responses by inducing HO-1 expression via Nrf2 activation. (-) - (E) -Guggulsterone exhibits antibacterial activities against Bacillus subtilis, Staphylococcus aureus and Pseudomonas aeruginosa. (-) - (E) -Guggulsterone has cardiac protective and antioxidant activities in rats.
Product Specifications
CAS Number
39025-24-6
Product Name Alternative
(E) -Guggulsterone (Standard)
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
Type
Reference Standards
Related Pathways
Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Infection; Endocrinology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/minus-e-guggulsterone-standard.html
Smiles
C/C=C1C(C[C@@]2([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]/12C)=O)=O
Molecular Formula
C21H28O2
Molecular Weight
312.45
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
GP210 (NUP210) (NM_024923) Human Recombinant Protein
![HDAC8 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1B2]](https://cdn.genprice.uk/products/937/6868c3f4994c49e6dc402cac/imageurl/ta809667bm.webp)