LIMPII Recombinant Rabbit Monoclonal Antibody [PSH03-25]
Lysosomal integral membrane protein 2 (LIMP-2) is a protein that in humans is encoded by the SCARB2 gene. LIMP-2 is expressed in brain, heart, liver, lung and kidney, mainly in the membrane of lysosome organelles; however, in cardiac muscle, LIMP-2 is also expressed at intercalated discs. LIMP-2 in a membrane protein in lysosomes that functions to regulate lysosomal/endosomal transport. Mutations in LIMP-2 have been shown to cause Gaucher disease, myoclonic epilepsy, and action myoclonus–renal failure syndrome. Abnormal levels of LIMP-2 have also been found in patients with hypertrophic cardiomyopathy.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
SCARB2, CD36L2, LIMP2, LIMPII
Swiss Prot
Q14108 Human, O35114 Mouse, P27615 Rat
Cellular Locus
Lysosome membrane.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat,Monkey
Immunogen
Recombinant protein within human LIMPII aa 5-459 / 478.
Isotype
IgG
Clone
PSH03-25
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Cell
Positive Control
Concentration
1 mg/mL
Dilution
WB: 1:2,000-1:5,000 ;IHC-P: 1:10,000 ;IF-Cell: 1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 54 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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