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MG-101

Product Specifications

UNSPSC Description

MG-101 (ALLN) is an inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with Kis of 190, 220, 150 and 500 pM, respectively. MG-101 induces apoptosis and inhibits tumor growth, it can be used for the research of colon cancer[1].

Target Antigen

Apoptosis; Proteasome

Type

Reference compound

Related Pathways

Apoptosis;Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/MG-101.html

Purity

98.0

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(N[C@H](C=O)CCCC)[C@@H](NC([C@@H](NC(C)=O)CC(C)C)=O)CC(C)C

Molecular Weight

383.53

References & Citations

[1]Li SZ, et al. ALLN hinders HCT116 tumor growth through Bax-dependent apoptosis. Biochem Biophys Res Commun. 2013 Jul 26;437(2):325-330.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-18964/MG-101-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-18964/MG-101-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

110044-82-1

Available Sizes

Curated Selection

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