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Mito-Rh-S

Product Specifications

UNSPSC Description

Mito-Rh-S is a ratiometric near-infrared (NIR) fluorescent probe that detects the fluctuation of mitochondrial HClO levels during ferroptosis in hepatocellular carcinoma (HCC)[1].

Target Antigen

Ferroptosis; Fluorescent Dye

Type

Dye Reagents

Related Pathways

Apoptosis;Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mito-rh-s.html

Solubility

10 mM in DMSO

Smiles

CCN1C(C=CC=C2)=C2SC(C=C3/C=C4C5=[O+]C6=CC(N(CC)CC)=CC=C6C(C7=C(C(O)=O)C=CC=C7)=C5CCC/4)=C1C=C3OC.Cl[O-]

Molecular Weight

695.27

References & Citations

[1]Bo Zhao, et al. Ratiometric Near-Infrared Fluorescent Probe Monitors Ferroptosis in HCC Cells by Imaging HClO in Mitochondria. Anal Chem. 2024 Apr 16;96(15):5992-6000.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-D2312/Mito-Rh-S-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-D2312/

Clinical Information

No Development Reported

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