Mito-Rh-S
Mito-Rh-S is a ratiometric near-infrared (NIR) fluorescent probe that detects the fluctuation of mitochondrial HClO levels during ferroptosis in hepatocellular carcinoma (HCC) [1].
Product Specifications
UNSPSC
12171500
Target
Ferroptosis; Fluorescent Dye
Type
Dye Reagents
Related Pathways
Apoptosis; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mito-rh-s.html
Solubility
10 mM in DMSO
Smiles
CCN1C(C=CC=C2)=C2SC(C=C3/C=C4C5=[O+]C6=CC(N(CC)CC)=CC=C6C(C7=C(C(O)=O)C=CC=C7)=C5CCC/4)=C1C=C3OC.Cl[O-]
Molecular Formula
C40H39ClN2O5S
Molecular Weight
695.27
References & Citations
[1]Bo Zhao, et al. Ratiometric Near-Infrared Fluorescent Probe Monitors Ferroptosis in HCC Cells by Imaging HClO in Mitochondria. Anal Chem. 2024 Apr 16;96 (15) :5992-6000.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Curated Selection
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