Mito-Rh-S

Mito-Rh-S is a ratiometric near-infrared (NIR) fluorescent probe that detects the fluctuation of mitochondrial HClO levels during ferroptosis in hepatocellular carcinoma (HCC) [1].

Product Specifications

UNSPSC

12171500

Target

Ferroptosis; Fluorescent Dye

Type

Dye Reagents

Related Pathways

Apoptosis; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mito-rh-s.html

Solubility

10 mM in DMSO

Smiles

CCN1C(C=CC=C2)=C2SC(C=C3/C=C4C5=[O+]C6=CC(N(CC)CC)=CC=C6C(C7=C(C(O)=O)C=CC=C7)=C5CCC/4)=C1C=C3OC.Cl[O-]

Molecular Formula

C40H39ClN2O5S

Molecular Weight

695.27

References & Citations

[1]Bo Zhao, et al. Ratiometric Near-Infrared Fluorescent Probe Monitors Ferroptosis in HCC Cells by Imaging HClO in Mitochondria. Anal Chem. 2024 Apr 16;96 (15) :5992-6000.