What is the catalog number for SAR7334?

The catalog number for SAR7334 is HY-15699.

What sizes are available for SAR7334?

SAR7334 is available in the following size(s): 5 mg, 10 mM - 1 mL, 10 mg, 50 mg, 100 mg.

How many pack sizes does SAR7334 come in?

SAR7334 is available in 5 different pack sizes.

SAR7334 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SAR7334?

SAR7334 is manufactured by QuantiMol.

What is the estimated delivery time for SAR7334?

Estimated delivery time for SAR7334 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for SAR7334?

The safety data sheet for SAR7334 is available here: http://file.medchemexpress.com/batch_PDF/HY-15699/SAR7334-SDS-MedChemExpress.pdf.

SAR7334

SAR7334 is a potent and specific TRPC6 inhibitor, inhibiting TRPC6 currents with IC50 of 7.9 nM.

Product Specifications

CAS Number

1333210-07-3

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

TRP Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/SAR7334.html

Purity

99.21

Solubility

DMSO : ≥ 370 mg/mL

Smiles

N[C@@H](C1)CCCN1[C@@H]2CC3=CC=CC=C3[C@H]2OC4=C(Cl)C=C(C#N)C=C4

Molecular Formula

C21H22ClN3O

Molecular Weight

367.87

Precautions

H302, H315, H319, H335

References & Citations

[1]Ilatovskaya DV, et al. The Role of Angiotensin II in Glomerular Volume Dynamics and Podocyte Calcium Handling. Sci Rep. 2017 Mar 22;7 (1) :299.|[2]Chauvet S, et al. Pharmacological Characterization of the Native Store-Operated Calcium Channels of Cortical Neurons from Embryonic Mouse Brain. Front Pharmacol. 2016 Dec 12;7:486.|[3]Maier T, et al. Discovery and pharmacological characterization of a novel potent inhibitor of diacylglycerol-sensitive TRPC cation channels. Br J Pharmacol. 2015 Jul;172 (14) :3650-60.