Cefotiam (hydrochloride)

Cefotiam (SCE-963) hydrochloride is a parenteral cephalosporin antibiotic. Cefotiam hydrochloride has broad-spectrum activity against Gram-positive and Gram-negative bacteria[1][2].

Product Specifications

CAS Number

[66309-69-1]

Product Name Alternative

SCE-963 (hydrochloride)

UNSPSC

12352005

Hazard Statement

H319

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

Neuroscience-Neuromodulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Cefotiam-hydrochloride.html

Purity

98.00

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 33.33 mg/mL (ultrasonic)

Smiles

O=C(C(N12)=C(CSC3=NN=NN3CCN(C)C)CS[C@]2([H])[C@H](NC(CC4=CSC(N)=N4)=O)C1=O)O.[H]Cl.[H]Cl

Molecular Formula

C18H25Cl2N9O4S3

Molecular Weight

598.55

Precautions

H319

References & Citations

[1]Iwahi T, et, al. Comparative activities of cefotiam and cefazolin against urinary tract infections with Proteus mirabilis in mice. Antimicrob Agents Chemother. 1980 Aug;18 (2) :257-63.|[2]Watt B, et, al. In-vitro activity of cefotiam against bacteria of clinical interest. J Antimicrob Chemother. 1982 Nov;10 (5) :391-5.